With Lama antibodies against the Coronavirus?

Lamas could possibly play a role in the fight against the new Coronavirus, SARS-CoV-2. The reason for this particular antibody, the produce, the animals, and the diseases have already been investigated for other virus such as the flu.

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Llamas produce antibodies two types of anti: One of them resembles the human antibodies, and the other is much smaller and more flexible. Long before the Corona broke out pandemic, involved researchers from Ghent in Belgium, and Austin in the United States with the effect of this small antibody to the so-called Spike Protein, which gives coronaviruses their name. They injected llamas Spike proteins of the pathogen from the SARS epidemic in 2002/03, and the MERS pathogen, and took the animals blood. What they found was not only an antibody that acted against both coronaviruses, but each one against the SARS and one directed against the MERS Virus. As the Coronavirus crisis broke out, tested the researchers, the effect of the small Lama antibodies to SARS-CoV-2. They showed for one of the two old antibody cross-reactivity. The against the "alte" SARS-CoV formed antibody also recognized the Spike Protein of SARS-CoV-2, and neutralized it.

Prophylactic administration planned

As co-author, Dr. Xavier Saelens from the University of Ghent, opposite the "New York Times" tells, the llama antibodies a still further feature. They are easy to manipulate, for example, can bodies with other antibodies, including human, linked, or fused be and still remain stable. The scientists emphasize that this antibody would be industrially in large quantities to produce. He could be administered, for example, as a preventive measure, such as employees in the health sector. This would be equivalent to a passive immunization, but would provide no lasting protection. Before the use in humans should be tested, how secure is the antibody in humans.

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